To open the door and escape from the room in the game featuring Plasticine men, follow these steps:

1. Explore the Room: Since you are in an art gallery with various themed rooms, start by thoroughly exploring the room you are in. Look for clues, items, or anything that might help you solve the puzzles.

2. Find the Differences: The game combines the "find the differences" genre. Look closely at the paintings and other elements in the room. There might be subtle differences between what you see and what should be there according to the clues or hints provided. These differences could be key to unlocking some of the 12 locks.

3. Solve the Puzzles: Engage with the various puzzles in the room. These puzzles could be related to the themes of the room (like retro cars, the Middle Ages, animals, or space). Solving these puzzles will likely provide you with keys or codes necessary to open the locks.

4. Use Plasticine Graphics to Your Advantage: The game's unique plasticine graphics might hide clues or interactive elements that blend into the environment. Be sure to interact with everything that looks out of place or different.

5. Listen to the Funny Music: Sometimes, games use audio cues to guide players. The funny music might change or provide hints when you are close to solving a puzzle or finding a key.

6. Combine Clues and Items: As you find items and solve puzzles, you'll need to combine these elements to unlock the 12 locks. Keep track of everything you find and think about how they might fit together.

7. Escape the Room: Once all 12 locks are opened, the door should unlock, allowing you and Liza to escape the art gallery and reunite with dad.

Remember, the key to escaping is to carefully observe, solve the puzzles, and use the unique features of the game to your advantage.